|
Microbes, bugs, germs, pathogens > Bacteria, viruses, sepsis, septic shock
A Short History Of Humans And Germs: The Golden Age Of Germs | Goats & Soda Video NPR 8 February 2017 YouTube https://www.youtube.com/watch?v=9bsqLmwAq-w
What is the difference between bacteria and viruses? 12 September 2012
Bacteria and viruses - What is the difference between bacteria and viruses? Video Healthchanneltv / cherishyourhealthtv 12 September 2012
In this animation, the differences between bacteria and viruses are explained.
How does a bacterium or virus enter the body?
And what are typical complaints of a viral or bacterial infection?
Finally, the different treatments for bacterial and viral infections are mentioned.
YouTube https://www.youtube.com/watch?v=s-HThHRV4uo
Bill Gates Pandemic TED 3 April 2015
Bill Gates: La prochaine épidémie ? Nous ne sommes pas prêts Video TED 3 April 2015 YouTube https://www.youtube.com/watch?v=6Af6b_wyiwI
Flu Attack! How A Virus Invades Your Body NPR 23 October 2009
Flu Attack! How A Virus Invades Your Body Video NPR 23 October 2009
When you get the flu, viruses turn your cells into tiny factories that help spread the disease.
In this animation, NPR's Robert Krulwich and medical animator David Bolinsky explain how a flu virus can trick a single cell into making a million more viruses.
YouTube https://www.youtube.com/watch?v=Rpj0emEGShQ
microbes USA
https://www.nytimes.com/2017/02/10/
Seeing the Invisible video Op-Docs NYT 17 September 2014 https://www.youtube.com/watch?v=mTzHxNMK0bU
http://judson.blogs.nytimes.com/2009/07/21/
http://www.nytimes.com/1995/05/09/
microbe hunters USA
http://www.nytimes.com/2011/08/30/
microbiologist USA
https://www.nytimes.com/2017/02/10/
germs
http://www.npr.org/sections/health-shots/2017/07/16/
https://www.reuters.com/article/2011/04/07/
virus, viruses > explainers USA
https://www.nytimes.com/2020/03/24/
https://www.theguardian.com/science/audio/2020/mar/24/
virus, viruses USA
https://www.npr.org/sections/goatsandsoda/2023/09/15/
https://www.npr.org/sections/goatsandsoda/2023/08/18/
https://www.nytimes.com/2020/03/24/
https://www.theguardian.com/science/audio/2020/mar/24/
https://www.npr.org/sections/health-shots/2019/05/22/
https://www.npr.org/sections/health-shots/2018/11/13/
https://www.npr.org/sections/goatsandsoda/2018/11/01/
https://www.npr.org/sections/codeswitch/2018/10/31/
https://www.npr.org/sections/goatsandsoda/2018/03/06/
https://www.nytimes.com/2018/02/23/
https://www.npr.org/sections/goatsandsoda/2017/11/16/
http://www.npr.org/sections/goatsandsoda/2017/09/20/
http://www.npr.org/sections/goatsandsoda/2017/06/21/
http://www.npr.org/sections/health-shots/2017/04/06/
http://www.npr.org/sections/goatsandsoda/2017/02/21/
http://www.npr.org/sections/goatsandsoda/2017/02/14/
http://www.npr.org/sections/goatsandsoda/2017/02/07/
http://www.npr.org/sections/goatsandsoda/2016/10/31/
http://www.npr.org/sections/health-shots/2016/08/29/
http://www.npr.org/sections/goatsandsoda/2016/08/25/
http://www.nytimes.com/video/world/americas/
http://www.nytimes.com/2016/01/29/
http://www.npr.org/blogs/health/2014/02/25/
http://www.nytimes.com/2013/07/18/
http://www.nytimes.com/2012/09/19/us/
https://www.youtube.com/watch?v=
strain USA
https://www.npr.org/sections/goatsandsoda/2023/09/15/
virus transmission UK
https://www.theguardian.com/business/2008/apr/13/
pass on UK
https://www.theguardian.com/theobserver/commentisfree/2021/may/02/
be exposed to the pathogen USA
https://www.nytimes.com/2020/05/07/
carry antibodies USA
https://www.nytimes.com/2020/05/07/
Septic shock: Diagnosis and treatment Khan Academy 25 November 2014
Septic shock: Diagnosis and treatment Video Circulatory System and Disease | NCLEX-RN | Khan Academy 25 November 2014 YouTube https://www.youtube.com/watch?v=ExJC8AoAczE
septic shock UK
Septic shock is a life-threatening condition that happens when your blood pressure drops to a dangerously low level after an infection.
Any type of bacteria can cause the infection.
Fungi such as candida and viruses can also be a cause, although this is rare.
At first the infection can lead to a reaction called sepsis.
This begins with weakness, chills, and a rapid heart and breathing rate.
Left untreated, toxins produced by bacteria can damage the small blood vessels, causing them to leak fluid into the surrounding tissues.
This can affect your heart's ability to pump blood to your organs, which lowers your blood pressure and means blood doesn't reach vital organs, such as the brain and liver.
People with a weakened immune system have an increased risk of developing septic shock.
This
includes: elderly people pregnant women people with long-term health conditions, such as diabetes, cirrhosis or kidney failure people with lowered immune systems, such as those with HIV or AIDS or those receiving chemotherapy
Symptoms of septic shock
Symptoms
of septic shock include: that makes you feel dizzy when you stand up a change in your mental state, such as confusion or disorientation
diarrhoea
nausea and vomiting
cold, clammy and pale skin
Septic shock is a medical emergency.
Dial 999 to ask for an ambulance if you think that you or someone in your care has septic shock.
Treating septic shock
You'll usually be admitted to an intensive care unit (ICU) so your body's functions and organs can be supported while the infection is treated.
In some cases treatment may start in the emergency department.
Treatment may include:
oxygen therapy
fluids given directly through a vein (intravenously)
medication to increase your blood flow
antibiotics
surgery (in some cases)
https://www.nhsinform.scot/
https://www.nhsinform.scot/
https://www.theguardian.com/society/2022/mar/04/
https://www.youtube.com/
sepsis UK
https://www.theguardian.com/society/
https://www.theguardian.com/politics/2023/sep/04/
https://www.theguardian.com/society/2022/mar/04/
sepsis / blood poisoning USA
Sepsis, which is sometimes called blood poisoning, is essentially the body's overreaction to an infection.
COVID-19 can trigger a similar reaction, known as a cytokine storm.
"Sepsis is one of the most common causes [of death] in the hospital, so finding a good treatment is extraordinarily important," says Dr. Jonathan Sevransky, a researcher and critical care physician at Emory University.
https://www.npr.org/sections/health-shots/2021/02/24/
https://www.npr.org/sections/health-shots/2021/02/24/
antibiotic > Zosurabalpin UK
Scientists have discovered an entirely new class of antibiotic that appears to kill one of three bacteria considered to pose the greatest threat to human health because of their extensive drug-resistance.
Zosurabalpin defeated highly drug-resistant strains of Carbapenem-resistant Acinetobacter baumannii (Crab) in mouse models of pneumonia and sepsis, and was being tested in human trials.
Crab is classified as a priority 1 critical pathogen by the World Health Organization, alongside two other drug-resistant forms of bacteria – Pseudomonas aeruginosa and Enterobacteriaceae.
https://www.theguardian.com/science/2024/jan/03
rotavirus
https://www.who.int/immunization/monitoring_surveillance/burden/estimates/
https://www.npr.org/sections/goatsandsoda/2018/11/01/
mosquito-borne virus > Chikungunya virus USA
https://www.npr.org/sections/goatsandsoda/2023/08/18/
Keystone virus USA
the Keystone virus (...) is carried by the Aedes atlanticus mosquito, a cousin to the Zika-spreading Aedes aegypti.
https://www.npr.org/2018/06/21/
https://www.npr.org/2018/06/21/
Herpes viruses USA
https://www.npr.org/sections/health-shots/2018/06/21/
Norovirus USA
Norovirus is responsible for roughly 1 in 5 cases worldwide of acute gastroenteritis.
The symptoms are pretty horrible: nausea, vomiting and diarrhea.
And it's very, very, very contagious.
It takes only one particle to infect a human, compared to roughly 50 to 100 particles of flu virus.
In countries with good health-care systems, a norovirus victim will have about three days of misery but likely recover.
But for young children and the elderly, especially in developing countries, the prognosis can be grim.
The Centers for Disease Control and Prevention estimate that 50,000 children a year, under age 5, die from norovirus, mainly in lower income countries.
The virus is particularly effective at finding victims in crowded places: hospitals, schools ... . and cruise ships, where everybody is living, eating and sharing activities in the same spaces.
https://www.npr.org/sections/goatsandsoda/2018/03/06/
mosquito-borne virus > dengue / breakbone fever USA
https://www.npr.org/sections/goatsandsoda/2019/05/03/7
http://www.npr.org/sections/goatsandsoda/2017/11/02/
virus > Lassa fever USA
"The most likely route of transmission continues to be spillover of viruses from the rodent reservoir to humans rather than extensive human-to-human transmission," the Nigeria Centre for Disease Control (NCDC) said in a report last week.
"Spillover" in non-scientific terms looks like this.
Rats carrying the Lassa virus scurry into people's houses, munch on their grain and pee all over the place including the grain.
Then people eat the grain and get sick.
Lassa, named for the town in Nigeria where it was first discovered in 1969, is a hemorrhagic fever, like Ebola.
Some people who get infected have few or no symptoms.
Others get what appears to be a mild flu or malaria.
Severe cases can lead to renal failure, deafness and, for pregnant women, spontaneous abortion.
While Lassa can be deadly, it has a lower fatality rate than Ebola. More than half of confirmed Ebola patients die versus roughly 20 percent of people with Lassa.
https://www.npr.org/sections/goatsandsoda/2018/03/19/
killer viruses USA
http://www.npr.org/sections/goatsandsoda/2017/09/20/
http://www.npr.org/sections/goatsandsoda/2017/03/26/
http://www.npr.org/sections/goatsandsoda/2017/02/14/
virus genes USA
http://www.npr.org/sections/health-shots/2017/04/06/
animals > viral risk USA
http://www.npr.org/sections/goatsandsoda/2017/06/21/
monkeypox USA
It causes a fever, and a rash, which can turn into painful, fluid-filled blisters on the face, hands and feet.
https://www.npr.org/sections/goatsandsoda/2017/11/16/
https://www.npr.org/sections/goatsandsoda/2022/05/27/
https://www.theguardian.com/news/audio/2022/may/25/
https://www.npr.org/sections/goatsandsoda/2022/05/18/
https://www.npr.org/sections/goatsandsoda/2017/11/16/
varicella zoster virus > shingles > vaccine UK / USA
Shingles, also known as herpes zoster, is an infection of a nerve and the skin around it.
It is caused by the varicella-zoster virus, which also causes chickenpox.
Shingles usually affects a specific area on one side of the body and does not cross over the midline of the body (an imaginary line running from between your eyes down past the belly button).
The main symptom is a painful rash that develops into itchy blisters that contain particles of the virus.
An episode of shingles typically lasts around two to four weeks, although around one in five people go on to develop nerve pain called postherpetic neuralgia in the affected area of skin. http://www.nhs.uk/conditions/shingles/Pages/Introduction.aspx
https://www.nhs.uk/conditions/shingles/
https://www.npr.org/sections/health-shots/2018/03/20/
http://www.npr.org/sections/health-shots/2015/07/13/
Nipah virus USA
The virus, first identified among pig farmers in Malaysia in 1999, likely jumped to humans at that time from infected pigs.
https://www.npr.org/sections/goatsandsoda/2023/09/15/
https://www.npr.org/sections/goatsandsoda/2023/09/15/
https://www.npr.org/sections/goatsandsoda/2018/07/01/
https://www.nytimes.com/2018/06/04/
Nipah virus > virus spill from bats into humans USA
https://www.npr.org/sections/goatsandsoda/2023/09/15/
human-human transmission USA
https://www.npr.org/sections/goatsandsoda/2023/09/15/
Nipah outbreak USA
https://www.npr.org/sections/goatsandsoda/2023/09/15/
herpes USA
http://www.npr.org/sections/health-shots/2016/01/22/
respiratory viruses USA
https://www.npr.org/sections/goatsandsoda/2018/09/08/
coronavirus > 2019 > SARS-CoV-2 USA
https://www.npr.org/sections/goatsandsoda/2021/05/20/
killer bug > coronavirus > 2012 Middle East Respiratory Syndrome coronavirus MERS UK / USA
https://www.cdc.gov/coronavirus/mers/index.html
https://www.npr.org/sections/goatsandsoda/2021/05/20/
https://www.npr.org/sections/health-shots/2014/05/14/
http://www.theguardian.com/lifeandstyle/2014/may/11/
http://www.npr.org/blogs/health/2014/05/02/
coronavirus > 2002 > SARS-CoV
https://www.npr.org/sections/goatsandsoda/2021/05/20/
measles USA
https://www.npr.org/2018/11/30/
Europe > measles USA
https://www.npr.org/sections/thetwo-way/2018/02/20/
http://www.npr.org/sections/goatsandsoda/2017/04/07/
http://www.npr.org/sections/goatsandsoda/2015/02/03/
infectious diseases > measles outbreak USA March 16, 2014
http://www.pbs.org/newshour/bb/
measles vaccine USA
http://www.npr.org/blogs/goatsandsoda/2015/05/07/
measles and whooping cough USA
http://www.npr.org/blogs/health/2014/01/25/
German measles / rubella causes only a mild illness in children, with a rash and sometimes a fever.
But when pregnant women catch rubella, their babies can develop serious birth defects, like heart problems, blindness and learning disabilities.
The virus can also trigger miscarriages early in a pregnancy. USA
http://www.npr.org/blogs/goatsandsoda/2015/04/30/
In the 1964-1965 rubella pandemic, an estimated 50,000 pregnant women in the United States were exposed to rubella in pregnancy, resulting in miscarriages, stillbirths, and 20,000 babies born with congenital rubella syndrome, which caused blindness, deafness, brain and heart damage.
At the height of the pandemic, an estimated 1 out of every 100 babies born in Philadelphia was afflicted.
A vaccine for rubella was introduced in the 1970s, so parents no longer have to live in fear.
http://www.npr.org/blogs/goatsandsoda/2015/04/30/
https://www.nytimes.com/2018/11/12/
https://www.npr.org/sections/thetwo-way/2018/02/20/
http://www.npr.org/sections/health-shots/2016/01/30/
http://www.npr.org/blogs/goatsandsoda/2015/04/30/
wipe out USA
http://www.npr.org/blogs/goatsandsoda/2015/04/30/
yellow fever UK
https://www.theguardian.com/global-development/2016/aug/16/
yellow fever USA
https://www.npr.org/sections/codeswitch/2018/10/31/
ticks > virus > Crimean-Congo hemorrhagic fever
In a large swath of the world, animals, including cows, sheep and goats, can carry a nasty virus: Crimean-Congo hemorrhagic fever.
They get it from ticks. The animals don't show symptoms, but if a person gets the virus it can make them really sick, with a headache, fever, severe bruising and bleeding.
Up to a third of patients die, usually within two weeks.
There's no vaccine for people or animals, and although an antiviral medication has shown promise in studies, the only proven treatment is supportive care.
http://www.npr.org/sections/goatsandsoda/2016/09/11/
http://www.npr.org/sections/goatsandsoda/2017/07/13/
http://www.npr.org/sections/goatsandsoda/2016/09/11/
cancer > causes 2013-2014
Cancers have many causes.
One is simply the process of ageing, which gives more time for mutations to occur, and this explains why cancer risk increases with age.
In addition, some cancers occur from inheriting unlucky gene that interfere with your cells' ability to repair mutations or to stop replicating.
Another common and widespread set of causes for cancer includes toxins, radiation and other environmental agents that provoke potentially carcinogenic mutations.
A few cancers are caused by viruses.
http://www.theguardian.com/society/2013/sep/22/
http://www.theguardian.com/society/2014/jan/08/
http://www.theguardian.com/society/2013/sep/22/
human papillomavirus HPV
the cause of most cervical cancer UK / USA
https://www.theguardian.com/society/
https://www.theguardian.com/society/2017/jul/19/
http://www.npr.org/sections/health-shots/2016/02/01/
http://www.npr.org/blogs/health/2014/02/03/
http://www.npr.org/blogs/health/2013/11/07/
http://www.npr.org/blogs/health/2013/11/07/
http://www.nytimes.com/2013/07/19/
http://www.guardian.co.uk/society/2013/jun/04/
http://www.nytimes.com/2013/06/04/
http://www.guardian.co.uk/news/datablog/2013/jun/02/
http://www.guardian.co.uk/society/2010/oct/17/
coronaviruses USA
https://www.npr.org/sections/goatsandsoda/2021/05/20/
New coronavirus – Q&A 2013 UK
http://www.guardian.co.uk/science/2013/may/13/
Meningitis > Viral meningitis / Bacterial meningitis
by a viral or bacterial infection.
and least serious type.
Bacterial meningitis is rare, but can be very serious if not treated.
Several different viruses and bacteria can
cause meningitis, including: there are several different types, called A, B, C, W, X, Y and Z
pneumococcal bacteria Haemophilus influenzae type b (Hib) bacteria
enteroviruses – viruses that usually only cause a mild stomach infection
the mumps virus
the herpes simplex virus – a virus that usually causes cold sores or genital herpes
A number of meningitis vaccinations provide protection against many of the infections that can cause meningitis.
How meningitis is spread
The viruses and bacteria that
cause meningitis can be spread through: coughing kissing sharing utensils, cutlery and toothbrushes
The infection is usually spread by people who carry these viruses or bacteria in their nose or throat, but are
not ill themselves. by
someone with meningitis, although this is less common. - 8 March 2019
https://www.nhs.uk/conditions/meningitis/causes/
meningitis USA
http://www.npr.org/blogs/health/2013/12/12/
viral diseases > polio, hepatitis and mononucleosis USA
https://www.nytimes.com/2021/01/25/
http://www.nytimes.com/2010/09/26/
http://www.theguardian.com/society/2005/apr/14/
outbreak > China > 2003 SARS outbreak UK / USA
https://www.theguardian.com/world/
https://www.npr.org/2023/03/15/
https://www.theguardian.com/science/2006/feb/25/
https://www.theguardian.com/world/2004/jan/03/
https://www.theguardian.com/world/2003/jun/24/
https://www.theguardian.com/world/2003/jun/02/
https://www.theguardian.com/society/2003/apr/21/
https://www.theguardian.com/world/2003/may/13/
https://www.theguardian.com/world/2003/may/12/
https://www.theguardian.com/world/2003/may/07/
https://www.theguardian.com/world/2003/may/05/
https://www.theguardian.com/world/2003/apr/27/
https://www.theguardian.com/world/2003/apr/24/
https://www.theguardian.com/society/2003/apr/21/
https://www.theguardian.com/world/2003/apr/09/
spread USA
https://www.nytimes.com/2018/06/04/
http://www.npr.org/sections/goatsandsoda/2016/10/31/
http://www.npr.org/blogs/health/2014/05/02/
carry the disease
the spread of the virus
gradual spread USA
http://www.npr.org/sections/goatsandsoda/2016/02/05/
contagion USA
http://www.nytimes.com/2011/09/16/
http://www.nytimes.com/2011/09/12/
epidemic UK
https://www.theguardian.com/science/2016/may/23/
epidemic > Black Death UK
https://www.theguardian.com/science/2016/may/23/
tripledemic USA
https://www.npr.org/2022/12/11/
pandemic USA
http://www.npr.org/sections/goatsandsoda/2017/03/26/
http://www.npr.org/sections/goatsandsoda/2017/03/17/
http://www.npr.org/sections/goatsandsoda/2017/02/21/
http://www.npr.org/sections/goatsandsoda/2017/02/14/
http://www.npr.org/sections/goatsandsoda/2016/01/13/
virologist USA
https://www.nytimes.com/2020/03/24/
virologist > USA > Robert Merritt Chanock 1924-2010
http://www.nytimes.com/2010/08/05/
stem
infectious diseases USA
http://www.nytimes.com/2011/09/16/
hyperinfectious disease world USA
http://www.npr.org/sections/goatsandsoda/2017/02/07/
be tested for N
be treated with N
take the utmost precautions and preparations
virologist USA
http://www.nytimes.com/2013/04/21/us/
Evelyn Ruth Maisel USA 1921-2023
Evelyn M. Witkin (...) discovered how DNA repairs Itself
Her findings led to breakthroughs in the treatment of cancer and in the understanding of the mechanics of evolution.
(...)
In a career that began at the dawn of modern genetic research in the late 1940s, Dr. Witkin explored the ways in which radiation both damaged DNA and generated a repair mechanism, what she came to call the SOS response.
The repair mechanism produces an enzyme that in turn creates replacement parts for the damaged DNA.
But it’s an imperfect process that can at times turn out slightly different versions, or mutations
— what scientists call mutagenesis.
Her insight into the SOS response, which Dr. Witkin developed with Miroslav Radman, then a scientist at the Free University of Brussels, shed new light on how solar radiation and chemicals in the environment affect
humans’ genetic makeup.
“She discovered the first coordinated response to stress in cells,” Joann Sweasy, a geneticist at the University of Arizona who studied under Dr. Witkin, said in a phone interview.
“And that’s so incredibly important for understanding evolution, and for understanding mutagenesis in terms of tumors.”
Dr. Witkin was still a graduate student at Columbia when she spent the summer of 1944 working at the Cold Spring Harbor Laboratory, on the north shore of Long Island.
Though she had no background in microbiology — her research until then had been with fruit flies — on her first day there she was assigned to generate mutations in cultures of the bacteria E. coli.
She placed several under a germicidal ultraviolet lamp.
Almost all of them died.
But four colonies survived.
“At this point, I asked, ‘Why did they survive? Maybe a mutation made them resistant,’”
Dr. Witkin told The New York Times
https://www.nytimes.com/2023/07/13/
https://www.nytimes.com/2023/07/13/
https://www.nytimes.com/2015/12/15/
James Joseph Rahal USA 1933-2011
infectious-disease specialist who raised early alarms about the rise of drug-resistant bacteria in hospitals, and who emerged as a leading expert in the treatment of West Nile virus after the Queens community where he worked became the epicenter of a deadly outbreak in 1999
http://www.nytimes.com/2011/06/15/nyregion/
viruses > polio > vaccination drive USA
https://www.nytimes.com/2024/09/01/
Andy Singer No Exit Cagle / Politicalcartoons.com 18 December 2006
Corpus of news articles
Health > Microbes, bugs, germs, pathogens
Bacteria, viruses, septic shock
The Real Threat of ‘Contagion’
September 11, 2011 The New York Times By W. IAN LIPKIN
I ADMIT I was wary when I was
approached, late in 2008, about working on a movie with the director Steven
Soderbergh about a flulike pandemic. It seemed that every few years a filmmaker
imagined a world in which a virus transformed humans into flesh-eating zombies,
or scientists discovered and delivered the cure for a lethal infectious disease
in an impossibly short period of time. W. Ian Lipkin is a professor of epidemiology and a professor of neurology and pathology at Columbia University.
The Real Threat of ‘Contagion’,
Explore more on these topics Anglonautes > Vocapedia
USA > prescription opioid painkillers
wildlife > insects > culicidae > mosquitoes
Related > Anglonautes
|
|